Advance Search
HUANG Lurong, LIN Qingping. Selection of surgical methods for cervical high-grade squamous intraepithelial lesions after menopause[J]. Journal of Clinical Medicine in Practice, 2023, 27(11): 28-31. DOI: 10.7619/jcmp.20230732
Citation: HUANG Lurong, LIN Qingping. Selection of surgical methods for cervical high-grade squamous intraepithelial lesions after menopause[J]. Journal of Clinical Medicine in Practice, 2023, 27(11): 28-31. DOI: 10.7619/jcmp.20230732
shu

Selection of surgical methods for cervical high-grade squamous intraepithelial lesions after menopause

  • Department of Gynecology, Xiamen Maternal and Child Health Care Hospital of Fujian Province, Women′s and Children′s Hospital Affiliated to Xiamen University, Xiamen, Fujian, 361000

More Information
  • Received Date: March 08, 2023
  • Revised Date: April 05, 2023
  • Available Online: June 24, 2023
    Graphical Abstract
    • Abstract
  • Objective 

    To explore the surgical methods for patients with cervical high-grade squamous intraepithelial lesions (HSIL) after menopause.

    Methods 

    Clinical materials of 293 patients with cervical cold-knife coning and hysterectomy for cervical HSIL were retrospectively analyzed. The pathological accuracy of colposcopic biopsy and coning resection in postmenopausal patients was compared, and the incidence rates of biopsy and extrascial total hysterectomy or extensive hysterectomy in postmenopausal patients with cervical HSIL were compared.

    Results 

    The pathological coincidence rate of postmenopausal women after coning was higher than biopsy. For cervical intraepithelial neoplasias (CIN) Ⅱ patients, there was no significant difference in the outcome of surgical selection based on biopsy and conical incision results (P>0.05). For CIN Ⅲ patients, treatment based on biopsy and conical incision results showed a significant difference in outcomes (P < 0.05).

    Conclusion 

    In postmenopausal women, the coincidence rate between post-biopsy pathology and final pathology is significantly lower than that between pathology and final pathology after conical resection. For postmenopausal women with CIN Ⅱ biopsy pathology and difficulty in conical resection surgery, total extrascial hysterectomy is recommended; for CIN Ⅲ patients, cold knife conical resection of cervix is recommended first, and further diagnosis and treatment plan is determined according to the conical pathology.

    • FullText(HTML)
    • References (13)
  • [1]
    HAMMER A, BLAAKAER J, DE KONING M N C, et al. Evidence of latent HPV infection in older Danish women with a previous history of cervical dysplasia[J]. Acta Obstet Gynecol Scand, 2022, 101(6): 608-615. doi: 10.1111/aogs.14362
    [2]
    LI X, LIU M H, JI Y R, et al. The effectiveness of cold-knife conization (CKC) for post-menopausal women with cervical high-grade squamous intraepithelial lesion: a retrospective study[J]. BMC Surg, 2021, 21(1): 241. doi: 10.1186/s12893-021-01238-8
    [3]
    曹倩文, 尤志学, 钱晓月, 等. 绝经后子宫颈高级别鳞状上皮内病变诊治方式的探讨[J]. 中华妇产科杂志, 2019, 54(6): 393-398. https://www.cnki.com.cn/Article/CJFDTOTAL-XDFC202203016.htm
    [4]
    李艳梅, 王建东. 绝经后宫颈上皮内瘤变宫颈锥切术后病灶残留相关危险因素分析[J]. 医学综述, 2021, 27(11): 2260-2263. https://www.cnki.com.cn/Article/CJFDTOTAL-YXZS202111032.htm
    [5]
    陈飞, 尤志学, 隋龙, 等. 阴道镜应用的中国专家共识[J]. 中华妇产科杂志, 2020, 55(7): 443-449.
    [6]
    BASU P, TAGHAVI K, HU S Y, et al. Management of cervical premalignant lesions[J]. Curr Probl Cancer, 2018, 42(2): 129-136. doi: 10.1016/j.currproblcancer.2018.01.010
    [7]
    CAO Q W, YOU Z X, QIAN X Y, et al. Discussion on the diagnosis and treatment of high-grade squamous intraepithelial lesions in post-menopausal women[J]. Zhonghua Fu Chan Ke Za Zhi, 2019, 54(6): 393-398.
    [8]
    BILIBIO J P, MONEGO H I, BINDA M L A, et al. Menopausal status is associated with a high risk for residual disease after cervical conization with positive margins[J]. PLoS One, 2019, 14(6): e0217562. doi: 10.1371/journal.pone.0217562
    [9]
    ZENG Y, JIANG T, ZHENG Y H, et al. Risk factors predicting residual lesion in subsequent hysterectomy following cold knife conization (CKC) for high-grade squamous intraepithelial lesion (HSIL)[J]. BMC Womens Health, 2022, 22(1): 358. doi: 10.1186/s12905-022-01939-z
    [10]
    GREENE A, HEATLEY M K. The appropriateness of examining the entire cervix histologically in hysterectomy specimens from women with a previous history of cervical intraepithelial neoplasia or dyskaryosis[J]. J Clin Pathol, 2001, 54(2): 155-157. doi: 10.1136/jcp.54.2.155
    [11]
    CHEUNG K W, CHEUNG V Y T. Hysterectomy for abnormal cervical smear when local excision is not possible[J]. J Low Genit Tract Dis, 2014, 18(3): 235-239. doi: 10.1097/LGT.0b013e3182a42d33
    [12]
    MIMOUN C, GLOAGEN S, MARCHAND E. Laparoscopic radical trachelectomy performed after sub-total hysterectomy in 7 steps (with video)[J]. Gynecol Obstet Fertil Senol, 2020, 48(5): 462-463.
    [13]
    SUN X Q, LEI H F, XIE X Y, et al. Risk factors for residual disease in hysterectomy specimens after conization in post-menopausal patients with cervical intraepithelial neoplasia grade 3[J]. Int J Gen Med, 2020, 13: 1067-1074.
    • Related Articles

  • Related Articles

    [1]LI Hongli, YAN Huili. Relationships of glucose metabolism with sex hormones and endometrial receptivity in patients with polycystic ovary syndrome at childbearing age[J]. Journal of Clinical Medicine in Practice, 2024, 28(10): 106-111. DOI: 10.7619/jcmp.20233856
    [2]ZHOU Lina, HAN Yanhua, GENG Tiantian, LIU Li. Research progress in effects of hyperandrogenin and insulin resistance on placental pathology of polycystic ovary syndrome
    [J]. Journal of Clinical Medicine in Practice, 2023, 27(11): 137-141. DOI: 10.7619/jcmp.20223478
    [3]DONG Yaguang, ZHU Lin, CHEN Haoyang. Research progress of complications of polycystic ovary syndrome in obstetric department and mechanisms[J]. Journal of Clinical Medicine in Practice, 2022, 26(9): 112-116. DOI: 10.7619/jcmp.20214639
    [4]CHEN Haixia, LI Jian, WU Fengyun, BAI Yueran, GU Bei, SONG Xiaohong, SUN Yu, CUI Guangxia, WANG Zijun, WANG Xiaoxue, YIN Cong, YANG Mukun, FAN Li, BAI Wenpei, JIANG Bo. Clinical pathway of ketogenic diet in the treatment of patients with polycystic ovary syndrome[J]. Journal of Clinical Medicine in Practice, 2021, 25(3): 5-7,32. DOI: 10.7619/jcmp.20210722
    [5]JIA Xiaolin, LI Na. Clinical efficiency of laparoscopic ovarian perforation combined with clomiphene citrate and human chorionic gonadotropin in treating infertility induced by polycystic ovary syndrome[J]. Journal of Clinical Medicine in Practice, 2019, 23(7): 102-105. DOI: 10.7619/jcmp.201907027
    [6]BAI Liran, LI Jian, NIU Litian, WANG Aili, WU Fengyun, BAI Wenpei, JIANG Bo. Preliminary report of a single-center clinical study for ketogenic diet intervention of polycystic ovary syndrome[J]. Journal of Clinical Medicine in Practice, 2019, 23(7): 2-5. DOI: 10.7619/jcmp.201907002
    [7]BAO Xudong, XU Yang, FU Rong. Effect of ethinylestradiol and cyproterone acetate tablets combined with metformin on hormone levels of patients with sterility caused by polycystic ovary syndrome[J]. Journal of Clinical Medicine in Practice, 2018, (1): 104-106,110. DOI: 10.7619/jcmp.201801032
    [8]MAYILA · Maimaiti, ZULIPIYA · Yiming. Clinical effect of clomiphene combined with human chorionic gonadotropin on ovulation induction in infertility patients with polycystic ovary syndrome[J]. Journal of Clinical Medicine in Practice, 2017, (17). DOI: 10.7619/jcmp.201717021
    [9]YIN Jiayao, YANG Ying. Study on modified ultra-long protocol in improving endometrial receptivity in infertile patients with polycystic ovary syndrome[J]. Journal of Clinical Medicine in Practice, 2016, (23): 75-77,81. DOI: 10.7619/jcmp.201623022
    [10]CAI Xiuli, YAO Jinyan, ZHANG Yijiao. Effect of Diane-35 combined with clomiphene on treatment of infertility caused by polycystic ovary syndrome[J]. Journal of Clinical Medicine in Practice, 2016, (15): 60-62. DOI: 10.7619/jcmp.201615017

  • Cited by

    Periodical cited type(14)

    1. 季晓丽，卢莹莹，赵小瑞. 酶联免疫法和金标法对HIV抗体的检测结果比较. 临床医学工程. 2024(03): 337-338 .
    2. 吴瑕. 化学发光免疫分析法与酶联免疫法检测艾滋病抗体的效果研究. 黑龙江中医药. 2023(02): 362-364 .
    3. 张婷婷. 溶血标本对化学发光免疫分析法检测HIV抗体检验结果的影响. 中国现代医生. 2022(08): 107-110 .
    4. 张缤月. 酶联免疫吸附法和实时荧光定量PCR法检验EB病毒的效果比较. 中国实验诊断学. 2022(07): 1078-1081 .
    5. 马伟刚. 溶血标本在应用化学发光免疫分析法检测HIV抗体时对检测结果的影响. 临床研究. 2022(09): 125-128 .
    6. 万琴. 不同免疫检验法抗HIV检测结果对比. 基层医学论坛. 2022(26): 55-57 .
    7. 江洋. 临床检验中化学发光免疫分析的应用效果分析. 中国实用医药. 2022(21): 87-89 .
    8. 王旭. 分析电化学发光免疫法与酶联免疫吸附试验法检测人类免疫缺陷病毒的临床效果. 中国实用医药. 2021(04): 46-48 .
    9. 刘凤. 艾滋病病毒感染实验检测方法研究进展. 应用预防医学. 2021(02): 185-188+193 .
    10. 张晨磊. 化学发光免疫分析法的研究进展. 医疗装备. 2021(14): 191-192 .
    11. 蔡贤惠. 电化学发光免疫分析与酶联免疫吸附试验检测甲型肝炎病毒Ig M抗体的对比评价. 中国医药指南. 2021(23): 74-75 .
    12. 武红斌. 不同酶免检测试剂检测抗HIV的结果比较. 临床医学研究与实践. 2020(24): 113-115 .
    13. 赵鸿翔. 人类免疫缺陷病毒抗体采用酶联免疫吸附法及电化学发光免疫分析法检测的效果. 中国医疗器械信息. 2020(24): 85-86 .
    14. 严建明，何宝贤，刘玉华. 酶联免疫法筛查HIV抗体应用于诊断艾滋病价值观察. 实用妇科内分泌电子杂志. 2020(18): 156+158 .

    Other cited types(2)

Catalog

    Get Citation
    PDF
    XML
    Article views (148) PDF downloads (8) Cited by(16)
    Turn off MathJax
    Article Contents
    Abstract
    References
    Related Articles

    © 2020 《实用临床医药杂志》编辑部

    Address: 江苏省扬州市江阳中路136号，扬州大学江阳路北校区14号楼201室China Pos: 225009Tel: 0514-87978917、87978989、87978807

    苏公网安备 32100302010246号

    Supported by: Beijing Renhe Information Technology Co., Ltd.   Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return