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GAO Feng, HUANG Xiangzhong. Clinical study of modified partial splenic artery embolization in the treatment of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt[J]. Journal of Clinical Medicine in Practice, 2023, 27(14): 95-98. DOI: 10.7619/jcmp.20231771
Citation: GAO Feng, HUANG Xiangzhong. Clinical study of modified partial splenic artery embolization in the treatment of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt[J]. Journal of Clinical Medicine in Practice, 2023, 27(14): 95-98. DOI: 10.7619/jcmp.20231771
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Clinical study of modified partial splenic artery embolization in the treatment of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt

  • Department of Intervention, Jiangyin Hospital Affiliated to Medical College of Southeast University, Jiangyin, Jiangsu, 214400

More Information
  • Received Date: May 31, 2023
  • Revised Date: June 15, 2023
  • Available Online: July 30, 2023
    Graphical Abstract
    • Abstract
  • Objective 

    To observe the effect of modified partial splenic artery embolization(MPSE) in the treatment of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt(TIPS).

    Methods 

    A retrospective analysis was performed for 10 patients with hepatic encephalopathy after TIPS treated with MPSE. Liver function indexes, main portal vein flow velocity and shunt flow velocity were compared before and 3 and 6 months after operation were compared.

    Results 

    All patients successfully completed the MPSE, and postoperative symptoms of abdominal pain occurred in 1 case, but no obvious surgery-related symptoms and complications were found in other cases. During the six-month postoperative follow-up, only 1 case of hepatic encephalopathy was not controlled. There were no significant differences in alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBIL), albumin (ALB) and main portal vein blood flow velocity at 3 and 6 months after operation (P>0.05). There were significant differences in shunt flow velocity 3 and 6 months after operation (P < 0.05).

    Conclusion 

    MPSE can reduce the shunt blood flow velocity after TIPS, and has the functions of flow limiting, thereby effectively controlling hepatic encephalopathy.

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    • References (21)
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