Research on the risk factors of anastomotic fistula after esophageal cancer surgery

ZHAO Yun; CUI Jian

doi:10.7619/jcmp.20232650

Journal of Clinical Medicine in Practice > 2024 > 28(1): 37-40. > DOI: 10.7619/jcmp.20232650

ZHAO Yun, CUI Jian. Research on the risk factors of anastomotic fistula after esophageal cancer surgery[J]. Journal of Clinical Medicine in Practice, 2024, 28(1): 37-40. DOI: 10.7619/jcmp.20232650

Citation:

ZHAO Yun, CUI Jian. Research on the risk factors of anastomotic fistula after esophageal cancer surgery[J]. Journal of Clinical Medicine in Practice, 2024, 28(1): 37-40. DOI: 10.7619/jcmp.20232650

Citation:

ZHAO Yun, CUI Jian. Research on the risk factors of anastomotic fistula after esophageal cancer surgery[J]. Journal of Clinical Medicine in Practice, 2024, 28(1): 37-40. DOI: 10.7619/jcmp.20232650

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Research on the risk factors of anastomotic fistula after esophageal cancer surgery

ZHAO Yun,
CUI Jian^,

Department of Thoracic Surgery, Beijing Chuiyangliu Hospital Affiliated to Tsinghua University, Beijing, 100022

More Information

Received Date: August 19, 2023
Revised Date: October 12, 2023
Available Online: January 22, 2024

Graphical Abstract

Abstract

Abstract

Objective
To investigate the risk factors of anastomotic fistula after esophageal cancer surgery.
Methods
The clinical data of 107 patients with esophageal cancer surgery were retrospectively analyzed, among whom 21 patients with anastomotic fistula after surgery were included in observation group, and 86 patients without anastomotic fistula after surgery were included in control group. The risk factors of anastomotic fistula after esophageal cancer surgery were identified by univariate analysis and multivariate Logistic regression analysis.
Results
Univariate analysis showed that age, hypoproteinemia, history of diabetes, preoperative neoadjuvant therapy, and anastomotic site were associated with anastomotic fistula after esophageal cancer surgery (P < 0.05); multivariate Logistic regression analysis showed that preoperative neoadjuvant therapy was an independent risk factor for postoperative anastomotic fistula in patients with esophageal cancer (OR=5.392; 95%CI, 1.335 to 30.382; P=0.020).
Conclusion
Preoperative neoadjuvant therapy is an independent risk factor for postoperative anastomotic fistula in patients with esophageal cancer. For patients with preoperative comorbid diseases, especially diabetes and hypoproteinemia, adequate preoperative preparation should be made.
- esophageal cancer surgery,
- anastomotic fistula,
- neoadjuvant therapy,
- hypoalbuminemia,
- diabetes,
- risk factors

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References (26)

References

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