Citation: | ZHANG Haiyu, ZHOU Yang, JIANG Yanping, LI Meihao, DU Juan. Investigation on prevalence of sarcopenia in elderly people and its correlation with geriatric frailty syndrome[J]. Journal of Clinical Medicine in Practice, 2024, 28(5): 111-115. DOI: 10.7619/jcmp.20233394 |
To investigate the prevalence of sarcopenia in the elderly people in a community of Chenghua District of Chengdu city and analyze its relationship with geriatric frailty syndrome.
A total of 586 elderly people in a community of Chenghua District of Chengdu city were selected as research objects for comprehensive geriatric assessment, including general data survey, anthropometric measurements (height, weight, grip strength, pace and skeletal muscle), and frailty screening scale survey. Incidence conditions of sarcopenia and geriatric frailty syndrome were evaluated, and the relationship between sarcopenia and geriatric frailty syndrome was analyzed.
Totally 83 cases were diagnosed as sarcopenia, and the prevalence of sarcopenia was 14.98%. There were no significant differences in gender, education level, smoking, alcohol consumption and basic diseases between the sarcopenia group and the normal group (P>0.05). Compared with the normal group, the sarcopenia group had a significant lower ratio of patients aged 60 to 74 years old, a significant higher ratio of patients aged 75 to 84 years old and ≥85 years old, and a significant higher incidence of geriatric frailty syndrome (P < 0.05). Compared with the normal group, the sarcopenia group had significant lower grip strength, pace, skeletal muscle mass of the four limbs, and appendicular skeletal muscle index (ASMI) (P < 0.05). Multivariate analysis showed that age, body mass index (BMI) and geriatric frailty syndrome were influencing factors for sarcopenia (P < 0.05).
Prevalence of sarcopenia in the elderly people in a community of Chenghua District of Chengdu city is relatively high, and sarcopenia is closely correlated with the occurrence of geriatric frailty syndrome.
[1] |
赵伟伟, 王柳清, 张守成, 等. 感觉器官功能退化与认知功能障碍[J]. 国际老年医学杂志, 2019, 40(5): 318-321. doi: 10.3969/j.issn.1674-7593.2019.05.016
|
[2] |
唐月颖, 海荣, 王静, 等. 老年人肌肉减少症的研究现状及应对[J]. 内蒙古医学院学报, 2020, 42(1): 96-99. https://www.cnki.com.cn/Article/CJFDTOTAL-NMYX202001037.htm
|
[3] |
姜珊, 康琳, 刘晓红. 2019亚洲肌少症诊断及治疗共识解读[J]. 中华老年医学杂志, 2020, 39(4): 373-376. doi: 10.3760/cma.j.issn.0254-9026.2020.04.002
|
[4] |
ABELLAN VAN KAN G, ROLLAND Y, BERGMAN H, et al. The I. A. N. A Task Force on frailty assessment of older people in clinical practice[J]. J Nutr Health Aging, 2008, 12(1): 29-37. doi: 10.1007/BF02982161
|
[5] |
DENT E, MORLEY J E, CRUZ-JENTOFT A J, et al. International clinical practice guidelines for sarcopenia (ICFSR): screening, diagnosis and management[J]. J Nutr Health Aging, 2018, 22(10): 1148-1161. doi: 10.1007/s12603-018-1139-9
|
[6] |
黄小江, 骆天炯. 肌少症危险因素及发病机制的研究进展[J]. 实用老年医学, 2020, 34(1): 81-85. doi: 10.3969/j.issn.1003-9198.2020.01.024
|
[7] |
AMARASEKERA A T, CHANG D, SCHWARZ P, et al. Vascular endothelial dysfunction may be an early predictor of physical frailty and sarcopenia: a meta-analysis of available data from observational studies[J]. Exp Gerontol, 2021, 148: 111260. doi: 10.1016/j.exger.2021.111260
|
[8] |
PATEL H P, SYDDALL H E, JAMESON K, et al. Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS)[J]. Age Ageing, 2013, 42(3): 378-384. doi: 10.1093/ageing/afs197
|
[9] |
BROWN J C, HARHAY M O, HARHAY M N. Sarcopenia and mortality among a population-based sample of community-dwelling older adults[J]. J Cachexia Sarcopenia Muscle, 2016, 7(3): 290-298. doi: 10.1002/jcsm.12073
|
[10] |
PETERMANN-ROCHA F, BALNTZI V, GRAY S R, et al. Global prevalence of sarcopenia and severe sarcopenia: a systematic review and meta-analysis[J]. J Cachexia Sarcopenia Muscle, 2022, 13(1): 86-99. doi: 10.1002/jcsm.12783
|
[11] |
吴琳瑾, 李静欣. 中国社区老年人肌少症患病率的Meta分析[J]. 现代预防医学, 2019, 46(22): 4109-4112, 4140. https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF201922018.htm
|
[12] |
SYDDALL H, ROBERTS H C, EVANDROU M, et al. Prevalence and correlates of frailty among community-dwelling older men and women: findings from the Hertfordshire Cohort Study[J]. Age Ageing, 2010, 39(2): 197-203. doi: 10.1093/ageing/afp204
|
[13] |
KARAKOUSIS N D, BILIOU S, PYRGIOTI E E, et al. Frailty, sarcopenia and diabetic kidney disease: where do we stand[J]. Int Urol Nephrol, 2023, 55(5): 1173-1181.
|
[14] |
郭帅, 罗雅楠, 郑晓瑛. 中国老年人口健康预期寿命性别差异多元变化趋势的研究: 2020-2050年[J]. 中华疾病控制杂志, 2023, 27(2): 201-208. https://www.cnki.com.cn/Article/CJFDTOTAL-JBKZ202302013.htm
|
[15] |
余嘉铭, 张艳, 黄一沁, 等. 上海市社区老年人躯体衰弱与肌少症的相关性研究[J]. 老年医学与保健, 2020, 26(4): 519-523. doi: 10.3969/j.issn.1008-8296.2020.04.004
|
[16] |
马丽娜. 老年衰弱综合征的发病机制[J]. 中华老年医学杂志, 2021, 40(3): 379-382.
|
[17] |
苏琳, 曹立, 海珊, 等. SARC-F量表及其改良版用于社区老人肌少症评估的筛查和诊断价值研究[J]. 实用老年医学, 2020, 34(11): 1132-1137. https://www.cnki.com.cn/Article/CJFDTOTAL-SYLA202011009.htm
|