Application value of point-of-care lung ultrasound scoring in selecting respiratory support treatment for neonatal infectious pneumonia

GAO Xingchen; HOU Weiwei; LYU Yuan; YANG Kaiting; PENG Nana; SHU Guihua

doi:10.7619/jcmp.20232858

Journal of Clinical Medicine in Practice > 2024 > 28(6): 56-59. > DOI: 10.7619/jcmp.20232858

GAO Xingchen, HOU Weiwei, LYU Yuan, YANG Kaiting, PENG Nana, SHU Guihua. Application value of point-of-care lung ultrasound scoring in selecting respiratory support treatment for neonatal infectious pneumonia[J]. Journal of Clinical Medicine in Practice, 2024, 28(6): 56-59. DOI: 10.7619/jcmp.20232858

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Application value of point-of-care lung ultrasound scoring in selecting respiratory support treatment for neonatal infectious pneumonia

Department of Neonatology, School of Clinical Medicine of Yangzhou University, Subei People's Hospital Affiliated to Yangzhou University, Yangzhou, Jiangsu, 225000

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Received Date: September 07, 2023
Revised Date: November 23, 2023
Available Online: April 01, 2024

Graphical Abstract

Abstract

Abstract

Objective
To investigate the application value of point-of-care lung ultrasound (POC-LUS) scoring in selecting respiratory support treatment modalities for neonatal infectious pneumonia (NIP).
Methods
A total of 89 NIP patients were selected as the study subjects and divided into control group (no assisted ventilation) with 46 cases, noninvasive group (noninvasive assisted ventilation) with 28 cases, and invasive group (invasive mechanical ventilation) with 15 cases based on the degree of dyspnea and blood gas analysis results. The POC-LUS scores of the three groups were compared, and the correlations of POC-LUS scores with arterial oxygen partial pressure [p_a(O₂)] and arterial carbon dioxide partial pressure [p_a(CO₂)] were analyzed. Receiver operating characteristic (ROC) curves were plotted to assess the predictive efficacy of POC-LUS scores for the need for noninvasive assisted ventilation or invasive mechanical ventilation in NIP patients.
Results
The POC-LUS scores of the noninvasive group and the invasive group were (31.7±7.3) and (42.1±8.0), respectively, which were higher than (21.5±7.3) of the control group. Additionally, the score of the invasive group was higher than that of the noninvasive group (P < 0.05). Correlation analysis revealed a significant negative correlation between POC-LUS scores and p_a(O₂) (r=-0.802, P < 0.05), and a significant positive correlation with p_a(CO₂) (r=0.807, P < 0.05). ROC curve analysis showed that the area under the curve (AUC) of POC-LUS scores for predicting the need for noninvasive assisted ventilation and invasive mechanical ventilation were 0.918 (95%CI, 0.862 to 0.973) and 0.938 (95%CI, 0.889 to 0.987), respectively. The sensitivity was 0.767 and 0.933, and the specificity was 0.935 and 0.824, with optimal cutoff values of 29.5 and 31.5, respectively.
Conclusion
POC-LUS scoring can quantitatively assess the severity of lung lesions in NIP patients and serves as a guiding tool for clinicians in selecting assisted ventilation treatment modalities.
- neonatal pneumonia,
- infectious pneumonia,
- point-of-care lung ultrasound,
- ultrasound scoring,
- respiratory support,
- assisted ventilation

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References (18)

References

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Application value of point-of-care lung ultrasound scoring in selecting respiratory support treatment for neonatal infectious pneumonia