Advance Search
LU Junjun. Effect of hysteroscopic endometrial electrotomy in treatment of patients with refractory dysfunctional uterine bleeding[J]. Journal of Clinical Medicine in Practice, 2020, 24(5): 117-120. DOI: 10.7619/jcmp.202005032
Citation: LU Junjun. Effect of hysteroscopic endometrial electrotomy in treatment of patients with refractory dysfunctional uterine bleeding[J]. Journal of Clinical Medicine in Practice, 2020, 24(5): 117-120. DOI: 10.7619/jcmp.202005032
shu

Effect of hysteroscopic endometrial electrotomy in treatment of patients with refractory dysfunctional uterine bleeding

  • Department of Gynecology and Obstetrics, Xi'an Baoshihua Changqing Hospital, Xi'an, Shaanxi, 710201

More Information
  • Received Date: December 04, 2019
  • Available Online: August 26, 2020
    Graphical Abstract
    • Abstract
  • Objective To explore the effect of hysteroscopic endometrial electrotomy in the treatment of patients with refractory dysfunctional uterine bleeding. Methods A total of 98 patients with refractory dysfunctional uterine bleeding were selected and randomly divided into control group and study group, with 49 cases in each group. Patients in the control group were treated with levonorgestrel intrauterine contraceptive system in the vagina, while patients in the study group were treated with hysteroscopic endometrial electrotomy. The endometrial thickness, menstrual volume, sex hormone indexes ［serum luteinizing hormone(LH), estradiol(E2), follicle stimulating hormone(FSH)］, hemoglobin level(Hb)and adverse reactions were compared between the two groups before treatment and 6 months after treatment. Results After 6 months of treatment, the endometrial thickness and menstrual volume of the study group were significantly smaller and less than those of the control group(P<0.01). After 6 months of treatment, the levels of LH and FSH in the control group were significantly higher than those in the study group(P<0.01), and the level of E2 was significantly lower than that in the study group(P<0.01). After 6 months of treatment, the Hb level in the study group was significantly higher than that in the control group(P<0.01). The incidence rate of adverse reactions in the study group was 2.04%, which was significantly lower than 16.33% in the control group(P=0.014). Conclusion Hysteroscopicendometrial electrotomy is effective in the treatment of patients with refractory dysfunctional uterine bleeding, which can not only effectively improve the symptoms of patients, correct the level of Hb, but also has no significant impact on the levels of sex hormones.
    • FullText(HTML)
    • References (15)
  • 雷洁. 宫腔镜子宫内膜电切术治疗功能性子宫出血的远期疗效观察[J]. 微创医学, 2019, 14(5): 618-619

    , 657.
    程艳芬, 夏利花, 倪燕. 宫腔镜在绝经后出血中的诊治分析[J]. 浙江创伤外科, 2019, 24(4): 746-748.
    刘雁林, 陈海燕, 王沛靓, 等. 宫腔镜子宫内膜电切术治疗功能失调性子宫出血的疗效及对患者性激素水平的影响[J]. 现代生物医学进展, 2019, 19(13): 2567-2570

    , 2582.
    胡慧, 王萍玲, 梁文通, 等. 诺舒手术治疗功能失调性子宫出血的有效性及安全性研究[J]. 中国妇产科临床杂志, 2019, 20(2): 172-173.
    郭宇鹏, 戴姝艳. 宫腔镜治疗慢性肾功能不全合并异常子宫出血患者回顾性分析[J]. 生物医学工程与临床, 2019, 23(2): 185-189.
    Ciavattini A, DI Giuseppe J, Clemente N, et al. Thickness of preperitoneal fat as a predictor of malignancy in overweight and obese women with endometrial polyps[J]. Oncol Lett, 2016, 11(3): 2278-2282.
    张建平, 唐文娟, 阳婷. 宫腔镜联合口服避孕药治疗剖宫产子宫瘢痕憩室110例疗效分析[J]. 中国医师杂志, 2019, 21(2): 286-288.
    刘芸. 宫腔镜电切术与刮宫术对子宫内膜息肉患者月经期及经量的影响[J]. 实用临床医药杂志, 2018, 22(13): 117-119.
    Grzechocinska B, Dabrowski F A, Chlebus M, et al. Expression of matrix metalloproteinase enzymes in endometrium of women with abnormal uterine bleeding [J]. Neuro Endocrinol Lett, 2018, 38(8): 537-543.
    魏雪敏, 夏艳, 张宏伟, 等. 宫腔镜整复术治疗剖宫产切口憩室致异常子宫出血的疗效评价[J]. 中国微创外科杂志, 2018, 18(12): 1073-1075.
    蒲文娟, 石梅, 董明亮, 等. 子宫内膜射频消融术治疗病理良性异常子宫出血疗效及对卵巢功能受损的影响[J]. 山西医药杂志, 2018, 47(17): 2009-2012.
    Brady P C, Soiffer R J, Ginsburg E S. Continuation of a Levonorgestrel Intrauterine Device During Hematopoietic Stem Cell Transplant: A Case Report[J]. Anticancer Res, 2017, 37(4): 1985-1987.
    徐凌燕, 魏民, 杨慧瑛. 宫腔镜子宫内膜电切术治疗功能失调性子宫出血的临床效果及对卵巢功能的影响[J]. 中国妇幼保健, 2017, 32(17): 4305-4307.
    汪莉, 徐珊. 宫腔镜下子宫内膜电切术在难治性功能失调性子宫出血治疗中的应用效果分析[J]. 中国性科学, 2017, 26(5): 49-52.
    叶淑珠. 诺舒子宫内膜切除术与经宫颈子宫内膜电切术治疗功能失调性子宫出血的比较[J]. 实用医学杂志, 2016, 32(12): 2001-2003.
    • Related Articles

  • Related Articles

    [1]CHEN Qi, YU Siyun, YANG Fengyun, YAO Jiayong, CHEN Rui, ZHANG Yu. Effect of Yishen Cupai Recipe in treatment of patients with polycystic ovary syndrome differentiated as type of renal deficiency with phlegm and stasis[J]. Journal of Clinical Medicine in Practice, 2021, 25(23): 99-102. DOI: 10.7619/jcmp.20213883
    [2]SONG Junya, WU Guirong, JIANG Yihua. Kuntai Capsule versus femoston in the treatment of patients with climacteric syndrome[J]. Journal of Clinical Medicine in Practice, 2020, 24(15): 102-104. DOI: 10.7619/jcmp.202015029
    [3]LIU Yan, WANG Jing. Efficiency evaluation of norethisterone combined with Bushen Guchong Zhixue Recipe in treatment of patients with dysfunctional uterine bleeding[J]. Journal of Clinical Medicine in Practice, 2020, 24(9): 69-72. DOI: 10.7619/jcmp.202009020
    [4]LUO Na. Effect of Liqi Huatan Xiaozheng Decoction combined with anti-progestin drugs on prognosis of uterine fibroids patients[J]. Journal of Clinical Medicine in Practice, 2019, 23(16): 89-92. DOI: 10.7619/jcmp.201916024
    [5]ZHENG Pingping, ZHU Qian. Efficiency of subtotal hysterectomy in treatment of patients with hysteromyoma[J]. Journal of Clinical Medicine in Practice, 2019, 23(14): 96-98. DOI: 10.7619/jcmp.201914026
    [6]HUANG Lijuan, XU Xiaofeng, LONG Cong, MAO Shiqin, DING Li, XU Qiubo. Application of anti-mullerian tubule hormone and sex hormone level in the evaluation of ovarian reserve function[J]. Journal of Clinical Medicine in Practice, 2018, (24): 55-57. DOI: 10.7619/jcmp.201824015
    [7]LI Dan, LI Juan, YUE Mingming, CHEN Fang, HUANG Dandan. Effect of wenjing decoction on serum follicle stimulating hormone, luteinizing hormone, estradiol, progesterone and testosterone of patients with menopathy of excess-cold syndrome[J]. Journal of Clinical Medicine in Practice, 2017, (19): 84-86,90. DOI: 10.7619/jcmp.201719024
    [8]YU Lan, REN Yu. Correlation between obesity and sex hormone level in male patients with type 2 diabetes mellitus[J]. Journal of Clinical Medicine in Practice, 2015, (1): 42-44. DOI: 10.7619/jcmp.201501013
    [9]LI Zhihong. Value of thyroid stimulating hormone inhibition therapy in differentiated thyroid carcinoma[J]. Journal of Clinical Medicine in Practice, 2013, (9): 107-108. DOI: 10.7619/jcmp.201309039
    [10]WANG Yun-ying, ZHANG Ping. The impact of replacement of different follicle-stimulating hormone during controlled ovarian stimulation on the result of in vitro fertilization and embryo transfer[J]. Journal of Clinical Medicine in Practice, 2011, (17): 55-57. DOI: 10.3969/j.issn.1672-2353.2011.17.018

  • Cited by

    Periodical cited type(23)

    1. 于洋，刘丽丽. 血清糖类抗原125 人附睾蛋白4及中性粒细胞与淋巴细胞比值的联合检测在子宫内膜异位症临床诊断中的价值. 中国妇幼保健. 2024(17): 3296-3299 .
    2. 武劼，周琛博，董雅雯. 卵巢囊肿患者性激素水平及预后的影响因素分析. 中国妇幼保健. 2024(20): 4038-4041 .
    3. 李婷娜，韦秋园，王晓暖，韩一栩. 卵巢子宫内膜样囊肿患者血清MLR、PLR、CA125的变化及临床意义. 中南医学科学杂志. 2023(02): 226-228+241 .
    4. 张小霞，林娟娟. 亮丙瑞林对弥漫型子宫腺肌症患者子宫体积、月经量及血清糖类抗原125的影响. 临床合理用药. 2023(20): 104-107 .
    5. 郭春芳，赵瑛. 曲肽与奥美拉唑联合用药方案治疗急性上消化道出血的疗效观察. 血栓与止血学. 2022(01): 75-76 .
    6. 雷静，马文娟. 凝血指标与炎性因子表达水平在子宫内膜异位症患者中的临床意义. 血栓与止血学. 2022(01): 71-72 .
    7. 李若冰，王翠丽. 凝血功能和炎症因子在中重度卵巢子宫内膜异位症发病中的诊断意义. 血栓与止血学. 2022(01): 79-80+83 .
    8. 张利明，白艳梅. 依诺肝素钠用于治疗D二聚体异常升高复发性流产的效果. 血栓与止血学. 2022(01): 84-85 .
    9. 王小兰，李美，童天夫，赵维英. 中重度子宫内膜异位症患者凝血指标、血清炎症因子变化及其临床意义. 中国计划生育学杂志. 2022(01): 129-134 .
    10. 王学博，杨建敏，杨然，郭小芬，冯磊，瞿小玲，李英霞. 卵巢型子宫内膜异位症患者外周血凝血指标、BDNF水平变化及对妊娠的影响. 实用预防医学. 2022(03): 371-375 .
    11. 秦敏. 血细胞及其衍生参数在子宫内膜异位症中的临床诊断价值. 系统医学. 2022(02): 69-72 .
    12. 袁铭，刘亚，戴春. 免疫球蛋白A肾病患者全身免疫炎症指数与低蛋白血症的关系. 实用临床医药杂志. 2022(11): 127-132 . 本站查看
    13. 张淑卿. 子宫内膜异位症诊断与治疗进展. 现代诊断与治疗. 2022(06): 799-801 .
    14. 马翠，自辉，薛潇. 宫腹腔镜-来曲唑对子宫内膜异位症患者血清炎症因子及ENA-78、MCP-1的影响. 中南医学科学杂志. 2022(05): 747-749 .
    15. 孔彬滟，姜秋慧. 曲普瑞林术后用药在接受腹腔镜卵巢巧克力囊肿剥除术患者中的应用效果. 中国民康医学. 2022(15): 67-70 .
    16. 贾璇，刘学良，吴国萍，柴连梅，车艳辞. 子宫内膜异位症患者血清LXA4、Ang-2及ENS水平与痛经、R-AFS分期的关系. 分子诊断与治疗杂志. 2022(09): 1545-1548 .
    17. 姜欣佐. 血浆D-二聚体定量检测在孕产妇中的运用分析. 黑龙江医学. 2022(20): 2444-2446 .
    18. 余文婷，徐晶，吴飞华，晏燕芳，尹平平. 中医药治疗子宫内膜异位症临床研究进展及机制概述. 中国当代医药. 2022(28): 38-41 .
    19. 张艳. 子宫内膜异位症凝血指标、炎性因子与盆腔粘连程度关系. 中国计划生育学杂志. 2021(05): 971-975 .
    20. 王颖颖. 冠心病患者血清CA125、CysC、OPG中的水平变化及意义. 中国卫生工程学. 2021(05): 839-840 .
    21. 刘亚曼，田熹，崔金华，张桂香. 子宫内膜异位症无创性诊断的研究进展. 现代肿瘤医学. 2021(24): 4419-4422 .
    22. 丁梦凯，顾振鹏，曹轶君，崔金秀，孙政. 血清CA125、炎症因子及凝血因子在子宫内膜异位症中的诊断价值. 中国现代医药杂志. 2021(11): 19-23 .
    23. 杜彦博，崔文娟，孙梅. 低剂量阿司匹林对内异症患者冻胚移植的影响. 实用妇科内分泌电子杂志. 2019(26): 1-3 .

    Other cited types(6)

Catalog

    Get Citation
    PDF
    XML
    Article views (342) PDF downloads (6) Cited by(29)
    Turn off MathJax
    Article Contents
    Abstract
    References
    Related Articles

    © 2020 《实用临床医药杂志》编辑部

    Address: 江苏省扬州市江阳中路136号，扬州大学江阳路北校区14号楼201室China Pos: 225009Tel: 0514-87978917、87978989、87978807

    苏公网安备 32100302010246号

    Supported by: Beijing Renhe Information Technology Co., Ltd.   Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return