Study on relevant factors influencing medicine-free remission rate after short-term continuous subcutaneous insulin infusion in newly diagnosed patients with type 2 diabetes metillus

Objective To analyze the relevant factors that influence the medicine-free re-mission rate after short-term continuous subcutaneous insulin infusion (CSII)in newly diagnosed patients with type 2 diabetes metillus (T2DM).Methods A total of 405 patients with T2DM hos-pitalized in our hospital from October 2003 to October 2012 served as the study objects,who were given CSII for 15 d and divided into success group (165 cases)and failure group (240 cases)based on the requirement of hypoglycemic agents after discharge from hospital.The relationship between ages,genders,body max index (BMI),fasting plasma glucose (FPG),glycated hemoglobin (HbA1c),ratio of 2 h C-peptide and fasting peptide (C2 /C0),attained time of plasma glucose and daily dosage of insulin during CSII with the clinical medicine-free remission rate after short-term CSII in patients with T2MD.Results Success group was evidently lower in FPG,HbA1c and daily dosage of insulin but obviously higher in C2 /C0 during CSII than failure group,and the differences were all statistically significant (P <0.01).Conclusion FPG,HbA1c and C2 /C0 can be used as the screening indexes for the diagnosis of T2DM patients treated with CSII,and T2DM patients with low FPG and HbA1c and high C2 /C0 are more suitable and should given CSII earlier so as to induce longer-term remission rate in clinic.