Distribution of pathogenic bacteria and drug resistance in patients with postoperative nosocomial infections in Department of Thoracic Surgery

SONG Huajie; GE Xiaoqing; ZHANG Jin; HOU Lu; YANG Kunpeng

doi:10.7619/jcmp.20201267

Journal of Clinical Medicine in Practice > 2021 > 25(3): 59-62, 68. > DOI: 10.7619/jcmp.20201267

SONG Huajie, GE Xiaoqing, ZHANG Jin, HOU Lu, YANG Kunpeng. Distribution of pathogenic bacteria and drug resistance in patients with postoperative nosocomial infections in Department of Thoracic Surgery[J]. Journal of Clinical Medicine in Practice, 2021, 25(3): 59-62, 68. DOI: 10.7619/jcmp.20201267

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Distribution of pathogenic bacteria and drug resistance in patients with postoperative nosocomial infections in Department of Thoracic Surgery

Department of Thoracic Surgery, Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450000

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Received Date: October 27, 2020
Available Online: March 03, 2021
Published Date: March 03, 2021

Graphical Abstract

Abstract

Abstract

Objective To analyze the distribution of pathogenic bacteria and drug resistance in patients with postoperative nosocomial infections in Department of Thoracic Surgery.
Methods The Chinese literatures about the detection of pathogenic bacteria or drug sensitivity test for postoperative nosocomial infection in patients with thoracic surgery published in recent 10 years were searched in CNKI database, Wanfang database and other relevant databases, and the relevant materials and data of the patients involved in literatures were screened and analyzed.
Results A total of 22 qualified literatures were included in this study. Among 12 938 cases with thoracic surgery, postoperative infections occurred in 2 562 cases, and the most frequently involved infection site was respiratory system. Totally 3 157 strains of pathogenic bacteria were detected, including 2 230 strains of Gram-negative bacteria (70.64%) with the top two strains of pseudomonas aeruginosa (19.90%) and klebsiella pneumoniae (15.68%), 749 strains of Gram-positive bacteria (23.73%) with the top two strains of staphylococcus aureus (9.72%) and enterococcus (4.53%), and 178 strains of fungi (5.64%). The results of drug sensitivity test showed that Gram-negative bacteria had good sensitivity to amikacin, imipenem and other antibiotics, and were generally resistant to sulfonamides, while Gram-positive bacteria had good sensitivity to sulfamethoxazole/trimethoprim and vancomycin, and were generally resistant to penicillin and cephalosporin.
Conclusion Gram-negative bacteria are the main pathogen of postoperative infections in Department of Thoracic Surgery, and fungal infection should not be ignored. In clinical practice, we should choose appropriate antibiotics according to the results of bacterial culture and drug sensitivity test.
- Department of Thoracic Surgery,
- postoperative infections,
- bacterial culture,
- drug sensitivity test

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