Research progress of umbilical cord mesenchymal stem cell-derived exosomes in treatment of tumor

LI Xiangying; GANG Qiaojian; MU Liyuan; SHENG Yingda; HA Xiaoqin

doi:10.7619/jcmp.20222117

Journal of Clinical Medicine in Practice > 2022 > 26(23): 108-112, 118. > DOI: 10.7619/jcmp.20222117

LI Xiangying, GANG Qiaojian, MU Liyuan, SHENG Yingda, HA Xiaoqin. Research progress of umbilical cord mesenchymal stem cell-derived exosomes in treatment of tumor[J]. Journal of Clinical Medicine in Practice, 2022, 26(23): 108-112, 118. DOI: 10.7619/jcmp.20222117

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Research progress of umbilical cord mesenchymal stem cell-derived exosomes in treatment of tumor

LI Xiangying^{1, 2, 3},
GANG Qiaojian^{2, 3, 4},
MU Liyuan^{2, 3},
SHENG Yingda^{1, 2, 3},
HA Xiaoqin^{2, 3, ,}

1.
School of Public Health of Gansu University of Traditional Chinese Medicine, Lanzhou, Gansu, 730000
2.
the 940 th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou, Gansu, 730050
3.
Key Laboratory of Stem Cell and Gene Medicine of Gansu Province, Lanzhou, Gansu, 730050
4.
the Second Clinical Medical School of Lanzhou University, Lanzhou, Gansu, 730000

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Received Date: July 10, 2022
Available Online: December 22, 2022

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Abstract

Abstract

Umbilical cord mesenchymal stem cells are multidirectional stem cells from the umbilical cord that can inhibit tumor development through exosomes. Exosomes secreted by umbilical cord mesenchymal stem cells play an anti-tumor role by participating in immune response, inhibiting tumor cell proliferation, reducing angiogenesis and improving drug sensitivity. However, there are few studies on the application of exosomes secreted by umbilical cord mesenchymal stem cells in tumor therapy. The paper reviewed the mechanism of action and application prospect of these drugs in tumor therapy.
- umbilical cord mesenchymal stem cells,
- exosome,
- tumor,
- treatment,
- drug delivery

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References (45)

References

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