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SHI Jianna, ZHOU Xindong, SUN Ke, SHI Haibo, CHEN Xia. Effects of Bushen Jiedu Formula combined with auricular pressure by coxherb seeds on cancer-induced pain and quality of life in patients with advanced colorectal cancer[J]. Journal of Clinical Medicine in Practice, 2024, 28(7): 41-44. DOI: 10.7619/jcmp.20240185
Citation: SHI Jianna, ZHOU Xindong, SUN Ke, SHI Haibo, CHEN Xia. Effects of Bushen Jiedu Formula combined with auricular pressure by coxherb seeds on cancer-induced pain and quality of life in patients with advanced colorectal cancer[J]. Journal of Clinical Medicine in Practice, 2024, 28(7): 41-44. DOI: 10.7619/jcmp.20240185
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Effects of Bushen Jiedu Formula combined with auricular pressure by coxherb seeds on cancer-induced pain and quality of life in patients with advanced colorectal cancer

  • Department of Oncology, Xishan District Hospital of Traditional Chinese Medicine of Jiangsu Province, Wuxi, Jiangsu, 214194

More Information
  • Received Date: January 09, 2024
  • Revised Date: March 11, 2024
  • Available Online: April 21, 2024
    Graphical Abstract
    • Abstract
  • Objective 

    To explore the effects of Bushen Jiedu Formula combined with auricular pressure by coxherb seeds on cancer pain and quality of life in patients with advanced colorectal cancer.

    Methods 

    A total of 120 patients with advanced colorectal cancer admitted to our hospital from June 2019 to May 2023 were included in the study, and were randomly divided into two groups. The control group (60 cases) received routine nursing care and the "three-step" analgesic method to intervene pain, while the observation group (60 cases) received treatment with Bushen Jiedu Formula combined with auricular pressure by coxherb seeds on the basis of the control group. Both groups were treated for one month. The Numerical Rating Scale (NRS) score, the therapeutic effect, the quality of life (QOL) score and the occurrence of adverse reactions were compared between the two groups before and after treatment, and the levels of substance P (SP), β-endorphin (β-EP) and prostaglandin E2(PGE2) of the two groups before and after treatment in serum were detected.

    Results 

    After treatment, the NRS score and the levels of SP, β-EP and PGE2 in the observation group were (2.23±0.64), (11.51±2.64) ng/mL, (78.64±9.46) ng/L and (41.90±6.32) ng/L, respectively, which were lower than (2.87±1.25), (15.64±2.42) ng/mL, (101.29±11.26) ng/L and (78.63±10.17) ng/L, respectively of the control group (P < 0.05). The total effective rate and QOL score of the observation group were 90.00% and (51.92±5.66), which were higher than 75.00% and (43.58±5.12), respectively of the control group (P < 0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05).

    Conclusion 

    The combination of Bushen Jiedu Formula and auricular pressure by coxherb seeds can obviously improve the cancer-induced pain of patients with advanced colorectal cancer, improve their quality of life, and have good safety.

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    • References (18)
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