Research advances in Coronavirus Disease 2019 and rheumatoid arthritis
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Graphical Abstract
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Abstract
Rheumatoid arthritis(RA) is an autoimmune disease characterized by chronic synovial inflammation,which eventually leads to different degrees of bone and cartilage erosion,even disability of joint.The patients of Coronavirus Disease 2019(COVID-19) can have musculoskeletal symptoms,and the mortality rate of critical patients is high.Cytokines play an important role in the pathogenesis of RA and COVID-19,the exact mechanism of which is unknown,and commonly used drugs of RA may guide the treatment of COVID-19.This article mainly reviewed the correlation between COVID-19 and RA in order to further improve the understanding of thepathogenesis,clinical manifestations,and treatment drugs of the disease and improve patients' outcomes.
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