WANG Mindan, WANG Hong, HAN Wenjuan, JIANG Yingying, ZHU Wenying, LU Yufen, HAN Xiaoyun. Effect of position adjustment combined with pressure flushing on flushing effect of laparoscopic ovarian endometriosis cyst removal[J]. Journal of Clinical Medicine in Practice, 2022, 26(23): 65-68. DOI: 10.7619/jcmp.20221658
Citation: WANG Mindan, WANG Hong, HAN Wenjuan, JIANG Yingying, ZHU Wenying, LU Yufen, HAN Xiaoyun. Effect of position adjustment combined with pressure flushing on flushing effect of laparoscopic ovarian endometriosis cyst removal[J]. Journal of Clinical Medicine in Practice, 2022, 26(23): 65-68. DOI: 10.7619/jcmp.20221658

Effect of position adjustment combined with pressure flushing on flushing effect of laparoscopic ovarian endometriosis cyst removal

More Information
  • Received Date: May 24, 2022
  • Available Online: December 22, 2022
  • Objective 

    To explore the effect of position adjustment combined with pressure irrigation on irrigation effect of laparoscopic ovarian endometriosis cyst removal.

    Methods 

    A total of 66 patients undergoing laparoscopic ovarian endometriosis cyst removal surgery under general anesthesia were selected as study objects, and were divided into control group(n=33) and observation group(n=33) by random number table method. The control group was given 1000 mL saline for washing at 30° degree in Trendelenburg position. The observation group was adjusted the surgical position when washing on the basis of the control group, and given pressed washing in whole process. The levels of carbohydrate antigen 125 (CA125) and vascular endothelial growth factor (VEGF) in peritoneal fluid were detected and compared between the two groups after pneumoperitoneum establishment (before intervention) and after irrigation (after intervention).

    Results 

    Before intervention, the levels of CA125 and VEGF in the peritoneal fluid in the two groups showed no statistically differences (P>0.05). After intervention, the levels of CA125 and VEGF in the peritoneal fluid were lower than intervention before, and were lower in the observation group than those in the control group(P < 0.05). The difference value before and after intervention in CA125 and VEGF levels in the observation group was greater than that of the control group (P < 0.05).

    Conclusion 

    Postural adjustment combined with pressurized irrigation during laparoscopic ovarian endometriosis cyst removal can reduce the levels of CA125 and VEGF in peritoneal fluid, reduce the residue of exfoliated intimal cells in the pelvic cavity, and decrease the probability of diffusion of inner membrane cells.

  • [1]
    WEI W, ZHANG X, TANG H, et al. Microbiota composition and distribution along the female reproductive tract of women with endometriosis[J]. Ann Clin Microbiol Antimicrob, 2020, 19(1): 15. doi: 10.1186/s12941-020-00356-0
    [2]
    ILHAN M, GÜRAĜAÇDERELI F T, AKKOL E K. Novel drug targets with traditional herbal medicines for overcoming endometriosis[J]. Curr Drug Deliv, 2019, 16(5): 386-399. doi: 10.2174/1567201816666181227112421
    [3]
    金海英. 腹腔镜手术联合GnRHa治疗卵巢子宫内膜异位囊肿伴不孕症的效果及对性激素水平的影响[J]. 中国实用医药, 2020, 15(23): 68-69. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSSA202023028.htm
    [4]
    王春梅, 肖新益. 腹腔镜剔除术与开腹囊肿剥脱术对卵巢子宫内膜异位囊肿患者卵巢储备及生育功能的影响[J]. 中外医学研究, 2020, 18(20): 132-133. https://www.cnki.com.cn/Article/CJFDTOTAL-YJZY202020056.htm
    [5]
    徐小敏, 江秀秀, 林俊. 腹腔镜保守手术联合GnRH-a对子宫内膜异位症患者卵巢功能及妊娠率影响研究[J]. 中国实用妇科与产科杂志, 2021, 37(7): 786-789. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGSF202107023.htm
    [6]
    洪花, 窦红梅, 王元杰, 等. 不同腹腔冲洗方式清除胃癌根治术脱落肿瘤细胞的效果[J]. 中华现代护理杂志, 2016, 22(24): 3497-3500. doi: 10.3760/cma.j.issn.1674-2907.2016.24.024
    [7]
    王丽姿, 李亚洁. 伤口冲洗压力的研究进展[J]. 护理研究, 2003, 17(2A): 134-136. https://www.cnki.com.cn/Article/CJFDTOTAL-SXHZ200303005.htm
    [8]
    王晓辉, 覃颖, 徐波. 子宫内膜异位症患者血清和腹腔液中VEGF、IL-6和CA125的表达及临床意义[J]. 中国妇幼保健, 2018, 33(20): 4573-4575. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFYB201820004.htm
    [9]
    谢幸, 孔北华, 段涛. 妇产科学学习指导与习题集[M]. 3版. 北京: 人民卫生出版社, 2018: 1-21.
    [10]
    中国医师协会妇产科医师分会, 中华医学会妇产科学分会子宫内膜异位症协作组. 子宫内膜异位症诊治指南(第三版)[J]. 中华妇产科杂志, 2021, 56(12): 812-824. https://xuewen.cnki.net/CCND-JIKA202201140050.html
    [11]
    邓霭辉. 血清炎性生物标记物在子宫内膜异位症患者血清中的表达及意义[J]. 河北医药, 2016, 38(24): 3685-3689, 3694. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYZ201624001.htm
    [12]
    唐玉霞, 金慧英, 夏雨虹, 等. 血清CA125在子宫内膜异位症复发诊断的价值[J]. 浙江临床医学, 2017(4): 749-750. https://www.cnki.com.cn/Article/CJFDTOTAL-JYYL202116014.htm
    [13]
    JIANG S J, LIANG S R, ZHANG X Q, et al. Research progress of IL-6/IL-6 receptor axis and its targeted inhibitors[J]. Chinese J Cell Mol Immunol, 2019, 35(6): 569-574.
    [14]
    郁平, 姬小凡, 王敏, 等. 腹腔镜手术联合亮丙瑞林、戊酸雌二醇治疗子宫内膜异位症效果及对腹腔液血管内皮生长因子、糖类抗原125水平影响[J]. 临床误诊误治, 2020, 33(2): 46-51. https://www.cnki.com.cn/Article/CJFDTOTAL-LCWZ202002012.htm
    [15]
    陈美玲, 柏红, 许里. 蒸馏水与生理盐水对腹腔肿瘤脱落细胞清除效果的比较[J]. 中国肿瘤外科杂志, 2012, 4(6): 381-382. https://www.cnki.com.cn/Article/CJFDTOTAL-ZLWK201206024.htm
    [16]
    张凤, 赵绍杰, 王金梅. 子宫内膜异位症患者腹腔镜术后应用促性腺激素释放激素类似物的效果观察[J]. 实用临床医药杂志, 2017, 21(19): 63-65. doi: 10.7619/jcmp.201719018
    [17]
    柳世香. 腹腔镜手术联合灭菌水囊腔冲洗治疗卵巢子宫内膜异位囊肿的疗效分析[J]. 中外医疗, 2018, 37(25): 66-67, 70. https://www.cnki.com.cn/Article/CJFDTOTAL-HZZZ201825025.htm
    [18]
    沈玉英. 地塞米松联合曲普瑞林腹腔镜术腔冲洗在治疗子宫内膜异位症中的应用效果[J]. 中国妇幼保健, 2017, 32(19): 4667-4669. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFYB201719022.htm
    [19]
    FRY D E. Pressure irrigation of surgical incisions and traumatic wounds[J]. Surg Infect: Larchmt, 2017, 18(4): 424-430.
    [20]
    张利平, 李娜. 雌激素阈值理论指导下的子宫内膜异位症术后巩固治疗研究[J]. 实用临床医药杂志, 2019, 23(5): 93-95, 99. doi: 10.7619/jcmp.201905026
    [21]
    赵亚. 地塞米松联合曲普瑞林及腹腔镜手术治疗子宫内膜异位症疗效观察[J]. 中国合理用药探索, 2019, 16(8): 77-79. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYYS201908024.htm
    [22]
    孙梅, 杨志新, 李瑞芹. 腹腔镜手术联合曲普瑞林治疗子宫内膜异位症临床疗效及对患者受孕率的影响[J]. 临床心身疾病杂志, 2022, 28(5): 40-44. https://www.cnki.com.cn/Article/CJFDTOTAL-LCSX202205009.htm
    [23]
    刘俊, 赵庆贺, 徐豪杰. 观察腹腔镜术后应用醋酸曲普瑞林治疗子宫内膜异位症的临床疗效与安全性[J]. 北方药学, 2019, 16(6): 170-171. https://www.cnki.com.cn/Article/CJFDTOTAL-BFYX201906134.htm
  • Related Articles

    [1]SHI Lihui, ZHANG Teng, LIANG Qiu, MEI Lijuan. Correlations of peripheral blood inflammatory and immune-related indicators with clinicopathological features and prognosis in breast cancer patients[J]. Journal of Clinical Medicine in Practice, 2025, 29(6): 75-79. DOI: 10.7619/jcmp.20245649
    [2]XU Xinlong, LI Huan, MA Kaixuan. Correlations of the expression of silencing information regulatory factor 2-related enzyme-1 and colony-stimulating factor 1 receptors with clinical features and prognosis in patients with colon cancer[J]. Journal of Clinical Medicine in Practice, 2024, 28(23): 70-74. DOI: 10.7619/jcmp.20242568
    [3]GUAN Shoutao, WANG Dengzheng, HU Fengchao, NING Linlin, AN Yue, GENG Hui, WANG Yuqiang. Expression levels of FOXO1 and SMAD4 in esophageal cancer tissues and their relationships with clinicopathological features and prognosis[J]. Journal of Clinical Medicine in Practice, 2024, 28(17): 9-14. DOI: 10.7619/jcmp.20240996
    [4]LIU Shenxiang, XU Yongcheng, YAN Xuebing, MAO Haiyan, YE Qian. Influence of clinicopathological characteristics of elderly patients with left and right colon cancer on prognosis[J]. Journal of Clinical Medicine in Practice, 2023, 27(4): 113-116, 122. DOI: 10.7619/jcmp.20223286
    [5]ZHOU Yizhi, ZHANG Zhongwei, XIANG Libin, LIU Yan, WANG Shuo, CAO Meinan. Expression of Rictor protein in tissue of colorectal cancer and its relationships with clinicopathological features and prognosis[J]. Journal of Clinical Medicine in Practice, 2022, 26(15): 80-83, 88. DOI: 10.7619/jcmp.20220770
    [6]WENG Zhihua, WANG Lei, ZHOU Jun. Value of Leu(CAG)-tRNA fragments in diagnosis and prognosis of lung adenocarcinoma and its relationship with clinical features[J]. Journal of Clinical Medicine in Practice, 2022, 26(15): 19-25. DOI: 10.7619/jcmp.20221478
    [7]DU Xiaodan, XU Weiguo, ZHU Jing, LI Lin, WU Junhua. Correlations of highly-expressed purinergic ligand-gated ion channel 7 purine receptor with clinicopathological features and prognosis in patients with resectable non-small cell lung cancer[J]. Journal of Clinical Medicine in Practice, 2022, 26(10): 77-82. DOI: 10.7619/jcmp.20214728
    [8]CHEN Hua, YAN Xu, SONG Shuling. Expressions of microRNA-185-5p and SOX13 in skin malignant melanoma and their clinical significance[J]. Journal of Clinical Medicine in Practice, 2022, 26(8): 54-59. DOI: 10.7619/jcmp.20214793
    [9]ZHAO Xiaohui, LI Shuang. Correlations between expressions of SEPT9 gene methylation, growth differentiation factor 15, carbohydrate antigen 199 and clinicopathologic features, prognosis in patients with colorectal cancer[J]. Journal of Clinical Medicine in Practice, 2021, 25(24): 52-56. DOI: 10.7619/jcmp.20213287
    [10]CHEN Jingzhi, MA Lili, FENG Yanyu. Expressions of circulating tumor cells, microribonucleic acid 1246, carbohydrate antigen 153 in breast cancer patients and their relationships with different clinicopathological features and prognosis[J]. Journal of Clinical Medicine in Practice, 2021, 25(22): 17-20, 25. DOI: 10.7619/jcmp.20211886

Catalog

    Article views (151) PDF downloads (6) Cited by()

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return