| Citation: |
LI Yuanyuan, CHEN Biquan, XIE Qilian. Role of zinc preparations in improving myocardial enzymes and cardiac troponin I of children with pediatric rotavirus enteritis[J]. Journal of Clinical Medicine in Practice, 2023, 27(11): 85-88. DOI: 10.7619/jcmp.20230373
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To explore the role of zinc preparations in improving myocardial enzymes and cardiac troponin I of children with pediatric rotavirus enteritis.
A total of 150 children with pediatric rotavirus enteritis were divided into control group and observation group according to the matching principles of basic between-group characteristics, with 75 cases in each group. The control group was treated with routine treatment, while the observation group was treated with routine treatment and zinc preparations (zinc gluconate), and both groups were treated for 7 days. The symptom improvement time, myocardial enzyme and cardiac troponin I levels, and clinical efficacy were compared between two groups.
The time for relieving diarrhea, vomiting and fever in the observation group was significantly shorter than that in the control group (P < 0.05). After treatment, the levels of creatine kinase, creatine kinase isozyme and lactate dehydrogenase in both groups decreased significantly, and these indexes in the observation group were significantly lower than those in the control group (P < 0.05). After treatment, the level of cardiac troponin I in both groups decreased significantly, and the cardiac troponin I level in the observation group was significantly lower than that in the control group (P < 0.05). The total effective rate was 97.33% in the observation group, which was significantly higher than 85.33% in the control group (P < 0.05).
Zinc preparations are effective in the treatment of children with pediatric rotavirus enteritis, which can quickly improve the symptoms and the levels of myocardial enzymes and cardiac protein troponin I.
| [1] |
韩静, 梅四红. 消旋卡多曲颗粒联合双歧杆菌三联活菌片对小儿轮状病毒性肠炎的疗效分析[J]. 河北医药, 2020, 42(2): 286-288. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYZ202002032.htm
|
| [2] |
徐小玲, 陈亚平, 杨乐乐, 等. 儿童轮状病毒肠炎的临床特点以及危险因素分析[J]. 中华实验和临床病毒学杂志, 2020, 34(3): 280-283. doi: 10.3760/cma.j.cn112866-20191031-00171
|
| [3] |
刘丽君, 程莹. 消旋卡多曲与秋泻灵颗粒联合肠道微生态调节剂治疗轮状病毒性肠炎疗效及对患儿外周血T淋巴细胞亚群水平的影响[J]. 陕西医学杂志, 2020, 49(8): 1013-1015, 1039. doi: 10.3969/j.issn.1000-7377.2020.08.025
|
| [4] |
白琼, 白冬梅, 李妮. 妈咪爱联合思密达治疗小儿轮状病毒性肠炎疗效及安全性分析[J]. 贵州医药, 2020, 44(5): 793-794. doi: 10.3969/j.issn.1000-744X.2020.05.055
|
| [5] |
卫应霞, 王斌, 刘利明. 消旋卡多曲颗粒联合锌制剂治疗儿童轮状病毒性肠炎的临床研究[J]. 深圳中西医结合杂志, 2021, 31(15): 158-160. https://www.cnki.com.cn/Article/CJFDTOTAL-SZZX202115074.htm
|
| [6] |
何绵宝, 周浩泉. 葡萄糖酸锌辅助治疗儿童轮状病毒性肠炎的安全性及有效性分析[J]. 淮海医药, 2021, 39(1): 39-41. https://www.cnki.com.cn/Article/CJFDTOTAL-HHYY202101012.htm
|
| [7] |
鄂丽莉. 葡萄糖酸锌联合消旋卡多曲在小儿轮状病毒性肠炎辅助治疗中的临床效果[J]. 中国药物与临床, 2021, 21(7): 1135-1137. https://www.cnki.com.cn/Article/CJFDTOTAL-YWLC202107037.htm
|
| [8] |
王立东, 张玉霞, 王茜. 维生素B2联合双歧杆菌乳杆菌三联活菌和蒙脱石散治疗小儿轮状病毒性肠炎的临床研究[J]. 现代药物与临床, 2021, 36(2): 355-358. https://www.cnki.com.cn/Article/CJFDTOTAL-GWZW202102030.htm
|
| [9] |
李丽拉, 王莉芬, 蔡亦斌, 等. 中性粒细胞CD11b、1, 25-(OH)2VitD3和γ干扰素在小儿轮状病毒性肠炎中的表达及与免疫功能的关系[J]. 临床和实验医学杂志, 2020, 19(14): 1500-1504. doi: 10.3969/j.issn.1671-4695.2020.14.013
|
| [10] |
邓有敬, 丁伟, 张芳玲, 等. 清热利湿方联合布拉氏酵母菌治疗儿童轮状病毒性肠炎效果及对血清AGEs、IL-6及NT-proBNP的影响[J]. 中国病原生物学杂志, 2022, 17(4): 451-454, 458. https://www.cnki.com.cn/Article/CJFDTOTAL-ZISC202204016.htm
|
| [11] |
蔡丽君, 王晓丽, 彭双勤. 果糖二磷酸钠联合布拉氏酵母菌对轮状病毒肠炎患儿的疗效及心肌损伤的影响[J]. 中国临床研究, 2020, 33(11): 1516-1519. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGCK202011016.htm
|
| [12] |
王新娟, 李惠芳, 王佩. 双歧杆菌三联活菌胶囊对轮状病毒感染肠炎患儿免疫功能及肠道菌群的影响[J]. 海南医学, 2021, 32(15): 1982-1985. https://www.cnki.com.cn/Article/CJFDTOTAL-HAIN202115021.htm
|
| [13] |
赵慧, 邓文, 李增清, 等. 葡萄糖酸锌联合维生素AD辅助治疗对不同病原菌感染肺炎儿童免疫功能及临床疗效的影响[J]. 实用医院临床杂志, 2020, 17(1): 14-17. https://www.cnki.com.cn/Article/CJFDTOTAL-YYLC202001004.htm
|
| [14] |
江萍, 胡敏, 李斌. 葡萄糖酸锌联合消旋卡多曲对轮状病毒性肠炎患儿机体微炎症状态及肠黏膜屏障功能的影响[J]. 中南医学科学杂志, 2021, 49(3): 318-321. https://www.cnki.com.cn/Article/CJFDTOTAL-HYYY202103015.htm
|
| [15] |
宁红卫, 于明丽. 双歧杆菌三联活菌散联合葡萄糖酸锌治疗轮状病毒性肠炎患儿的效果[J]. 河南医学研究, 2021, 30(36): 6845-6848. https://www.cnki.com.cn/Article/CJFDTOTAL-HNYX202136039.htm
|
| [16] |
杜华. 锌制剂联合常规药物对轮状病毒性肠炎患儿的治疗作用探讨[J]. 黑龙江中医药, 2021, 50(2): 63-64. https://www.cnki.com.cn/Article/CJFDTOTAL-HLZY202102049.htm
|
| [17] |
李燕, 邵利红. 双歧三联活菌联合重组人干扰素α1b对轮状病毒性肠炎患儿肠道菌群和心肌酶谱的影响[J]. 中国妇幼保健, 2021, 36(8): 1793-1796. https://www.cnki.com.cn/Article/CJFDTOTAL-ZFYB202108029.htm
|
| [18] |
范燕霞. 氨基酸注射液联合消旋卡多曲颗粒治疗儿童轮状病毒性肠炎的疗效及对心肌酶的影响[J]. 现代诊断与治疗, 2021, 32(18): 2902-2903. https://www.cnki.com.cn/Article/CJFDTOTAL-XDZD202118022.htm
|
| [19] |
孙蓓蓓, 封东进, 王光猛, 等. 葡萄糖酸锌颗粒联合消旋卡多曲颗粒对轮状病毒性肠炎患儿血浆炎性因子、心肌酶指标及免疫功能的影响[J]. 现代生物医学进展, 2020, 20(23): 4543-4546, 4551. https://www.cnki.com.cn/Article/CJFDTOTAL-SWCX202023031.htm
|
| [20] |
唐晓芳, 童晓玲, 安阳阳. 血清肌酸激酶同工酶、肌钙蛋白I及氨基末端脑利钠肽前体检测在小儿轮状病毒肠炎合并心肌损害的诊断价值[J]. 实用医院临床杂志, 2020, 17(4): 37-39. https://www.cnki.com.cn/Article/CJFDTOTAL-YYLC202004012.htm
|
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