| Citation: |
SHEN Hong, LEI Shu. Application effect of nursing intervention based on concept of enhanced recovery after surgery in patients with advanced rectal cancer after cytoreductive surgery combined with intraperitoneal perfusion chemotherapy[J]. Journal of Clinical Medicine in Practice, 2024, 28(7): 110-114. DOI: 10.7619/jcmp.20232986
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To observe the effect of nursing intervention based on concept of enhanced recovery after surgery (ERAS) in patients with advanced rectal cancer after cytoreductive surgery combined with intraperitoneal perfusion chemotherapy.
A total of 124 patients with intraperitoneal chemotherapy for rectal cancer were selected as study subjects, and randomly divided into observation group (n=62) and control group (n=62). The control group was treated with routine nursing intervention, and the observation group was treated with nursing intervention based on ERAS concept. Visual Analogue Scale (VAS) scores were compared between the two groups. The scores of Self Rating Anxiety Scale (SAS), Self Rating Depression Scale (SDS) and Quality of Life Questionary-Core 30 (QOL-C30) before and after intervention were compared between the two groups. The occurrence of adverse reactions and nursing satisfaction were compared between the two groups.
The VAS score of the observation group was significantly lower than that of the control group at the 2nd and 3rd chemotherapy (P<0.05). After intervention, SAS score and SDS score in two groups were significantly lower than before intervention, and the observation group was significantly lower than the control group (P<0.05). After intervention, the QOL-C30 scores of body function, role function, emotional function, cognitive function and social function in two groups were significantly higher than before intervention, and the observation group was significantly higher than the control group (P<0.05); symptom score of QOL-C30 in two groups was significantly lower than before intervention, and the observation group was significantly lower than the control group (P<0.05). After intervention, the incidence of adverse reactions in the observation group was 56.45%, which was significantly lower than 77.42% in the control group (P<0.05). After intervention, the nursing satisfaction score of the observation group was significantly higher than that of the control group (P<0.05).
Nursing intervention based on ERAS concept can effectively relieve pain and adverse emotions in patients with advanced rectal cancer undergoing cytoreductive surgery combined with intraperitoneal perfusion chemotherapy, reduce the incidence of adverse reactions, and improve quality of life, with high nursing satisfaction.
| [1] |
SAKAMOTO W, KANKE Y, ONOZAWA H, et al. Short-term outcomes of neoadjuvant chemotherapy with capecitabine plus oxaliplatin for patients with locally advanced rectal cancer followed by total or tumor-specific mesorectal excision with or without lateral pelvic lymph node dissection[J]. Fukushima J Med Sci, 2022, 68(2): 89-95. doi: 10.5387/fms.2022-07
|
| [2] |
熊剑勇, 张莉涓, 唐人, 等. 雷替曲塞用于结直肠癌腹膜转移患者术中腹腔灌注化疗的安全性研究[J]. 实用癌症杂志, 2021, 36(10): 1673-1676. https://www.cnki.com.cn/Article/CJFDTOTAL-SYAZ202110029.htm
|
| [3] |
张晓玲, 罗衡桂, 陈伟, 等. 加速康复外科管理模式在老年结直肠癌围手术期应用效果[J]. 中国普通外科杂志, 2022, 31(1): 132-138. https://www.cnki.com.cn/Article/CJFDTOTAL-ZPWZ202201015.htm
|
| [4] |
贾鑑慧. 常见消化系肿瘤诊治学[M]. 沈阳: 辽宁科学技术出版社, 2014: 74-79.
|
| [5] |
安松林, 张凯, 姬忠贺, 等. 肿瘤细胞减灭术联合腹腔热灌注化疗治疗结直肠癌腹膜癌的疗效[J]. 中华肿瘤杂志, 2021, 43(12): 1298-1303. https://www.cnki.com.cn/Article/CJFDTOTAL-DCGM202306018.htm
|
| [6] |
肖霞, 贺雪菲, 王小燕, 等. 精准营养疗法联合同理心护理对腹腔镜结直肠癌根治术患者营养状况及心理韧性的影响[J]. 川北医学院学报, 2022, 37(6): 820-824. doi: 10.3969/j.issn.1005-3697.2022.06.033
|
| [7] |
薛玉萍, 许蔚. 激励式护理联合正念减压训练在结直肠癌术后患者中的应用[J]. 中国医药导报, 2022, 19(1): 177-180. https://www.cnki.com.cn/Article/CJFDTOTAL-YYCY202201044.htm
|
| [8] |
郭丹丹, 李娜, 张娜, 等. 优质护理干预对腹腔热灌注化疗的晚期结直肠癌患者生活质量的影响[J]. 河北医药, 2019, 41(16): 2547-2549, 2553. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYZ201916038.htm
|
| [9] |
宋英莉, 杜成, 杨贺, 等. 互联网延续性护理对结直肠癌化疗患者心理状况及不良反应的影响[J]. 中国实用护理杂志, 2021, 37(20): 1545-1550.
|
| [10] |
孙兵, 车晓明(整理). 视觉模拟评分法(VAS)[J]. 中华神经外科杂志, 2012, 28(6): 645-645.
|
| [11] |
段泉泉, 胜利. 焦虑及抑郁自评量表的临床效度[J]. 中国心理卫生杂志, 2012, 26(9): 676-679. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXWS201209007.htm
|
| [12] |
夏蕾, 杨猛. 主体双元一体化的护理模式在胶质瘤术后患者生存状况的研究[J]. 山西医药杂志, 2017, 46(15): 1810-1812. https://www.cnki.com.cn/Article/CJFDTOTAL-SXYY201715015.htm
|
| [13] |
LI W C, ZHAO J K, FENG W Q, et al. Retrospective research of neoadjuvant therapy on tumor-downstaging, post-operative complications, and prognosis in locally advanced rectal cancer[J]. World J Gastrointest Surg, 2021, 13(3): 267-278. doi: 10.4240/wjgs.v13.i3.267
|
| [14] |
杨凯, 胡燕, 王洪健, 等. 进展期结直肠癌术中洛铂腹腔灌注化疗的临床疗效及安全性分析[J]. 海南医学, 2021, 32(14): 1810-1813. doi: 10.3969/j.issn.1003-6350.2021.14.011
|
| [15] |
宋晓凤, 李守淼, 李保中. 腹腔热灌注化疗治疗胃癌的护理[J]. 航空航天医药, 2010, 21(2): 263-264. https://www.cnki.com.cn/Article/CJFDTOTAL-HKHT201002099.htm
|
| [16] |
BOGANI G, SARPIETRO G, FERRANDINA G, et al. Enhanced recovery after surgery (ERAS) in gynecology oncology[J]. Eur J Surg Oncol, 2021, 47(5): 952-959. doi: 10.1016/j.ejso.2020.10.030
|
| [17] |
罗维民, 温翠婷, 胡丰良. 加速康复外科策略在老年结直肠癌腹腔镜手术治疗的应用及其对免疫功能和炎性因子的影响[J]. 中国普通外科杂志, 2019, 28(4): 512-518. https://www.cnki.com.cn/Article/CJFDTOTAL-ZPWZ201904024.htm
|
| [18] |
王莉, 梁冰, 杨慧. 基于循证的加速康复外科的集束化干预方案对结直肠癌根治术患者术后恢复及并发症的影响[J]. 癌症进展, 2021, 19(2): 207-210, 214. https://www.cnki.com.cn/Article/CJFDTOTAL-AZJZ202102025.htm
|
| [19] |
桂普国, 孙瑞平. 加速康复外科联合腹腔镜结直肠癌根治术对结直肠癌患者预后、免疫水平影响[J]. 医学临床研究, 2022, 39(1): 132-135.
|
| [20] |
ASHOK A, NIYOGI D, RANGANATHAN P, et al. The enhanced recovery after surgery (ERAS) protocol to promote recovery following esophageal cancer resection[J]. Surg Today, 2020, 50(4): 323-334. doi: 10.1007/s00595-020-01956-1
|
| 1. |
王晶一，郑娅，史海燕. 银杏二萜内酯葡胺注射液联合调督舒筋手法对急性脑梗死患者ET-1、S100β及血液流变学的影响. 中国基层医药. 2024(11): 1693-1698 .
| |
| 2. |
朱珊珊，崔丽，徐军伟. 银杏二萜内酯葡胺联合阿加曲班在急性脑梗死中的应用效果. 河南医学研究. 2023(11): 2043-2047 .
| |
| 3. |
卢长岭. 银杏二萜内酯葡胺在急性缺血性脑卒中患者中的应用. 实用中西医结合临床. 2023(18): 20-22+33 .
| |
| 4. |
周承升，赵浚乐. 依达拉奉联合银杏二萜内酯治疗脑梗死后功能障碍的效果. 内蒙古中医药. 2022(03): 109-111 .
| |
| 5. |
张怡. 双抗与银杏二萜内酯葡胺联合替罗非班治疗小分支脑动脉闭塞引发急性脑梗死的疗效对比. 当代临床医刊. 2022(03): 66-67 .
| |
| 6. |
郭娟娟. 银杏二萜内酯葡胺与阿司匹林在急性脑梗死中的治疗效果及对BI、NIHSS、QOLISP评分的影响分析. 中外医疗. 2022(09): 14-18 .
| |
| 7. |
李瑾，高晓红，王玉梅. 银杏二萜内酯葡胺对脑梗死合并多发性颅内动脉狭窄的影响. 中国社区医师. 2022(19): 55-57 .
| |
| 8. |
周安. 阿加曲班联合银杏二萜内酯葡胺注射液治疗后循环脑梗死的效果. 医学理论与实践. 2022(20): 3464-3466 .
| |
| 9. |
孙忠发，吴剑冰，尤东阳，孙强. 银杏二萜注射液对急性脑梗死溶栓患者认知功能与血液流变学的影响. 北方药学. 2022(11): 10-12 .
| |
| 10. |
李贞，蒋磊，徐维平. 242例住院患者银杏二萜内酯葡胺注射液合理用药分析. 中国药业. 2021(14): 111-113 .
|
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